COMMENTARY ON CHINESE STUDIES AND THE STUDY, XING ET AL. 2009

Professor Joel Brind (Baruch College, City University of New York) maintains that Chinese studies underestimate the risk because of the high prevalence of abortion in China. In his review of 10 prospective studies on the ABC link for the Journal of American Physicians and Surgeons in December, 2005, Professor Brind explained that it's hard to do an epidemiological study accurately in communist countries where exposure to abortion affects most of the study population. [1]

In the study, Xing et al., the prevalence of abortion is quite high at about 56% overall in this population. Because abortion is so prevalent in the population, women in the small, unexposed population (the comparison group) are a minority group and do not represent a typical population. Rather, they're atypical because they represent a high-risk subgroup. Women without abortions in China are more likely to be childless or to have late FFTPs, which are accepted risk factors for breast cancer.

The Chinese government has a one-child-per-couple policy in which women are forcibly aborted after FFTP. Over 90% of abortions are performed on women with a child. Childbearing is known to provide a reduction in risk over the long-term. Women with abortions have had their risk lowered because they have had early FFTPs (unlike Western nations where most abortions occur during the most carcinogenic time in a woman's life - before FFTP). Therefore, in a Chinese study, the protective effect of early FFTP masquerades as the protective effect of abortion.  An FFTP reduces risk by maturing 85% of the mother's cancer-susceptible breast lobules into permanently cancer-resistant lobules. The younger a woman is at FFTP, the lower her breast cancer risk is.

Reference:

1. Brind J. Induced abortion as an independent risk factor for breast cancer: A critical review of recent studies based on prospective data. J Am Phys Surg Vol. 10, No. 4 (Winter 2005) 105-110. Available at: < http://www.jpands.org/vol10no4/brind.pdf>.

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